تفاعل #1478584

ord-e8300acfe5a44cfebc4d75f95493ba60

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىin further process steps, the racemic mixture is separated
  2. 2
    أخرىD-pantolactone is subjected to a condensation reaction with β-alanine

الإجراء التجريبي

Pantothenic acid can be prepared by chemical synthesis, or biotechnologically by fermentation of suitable microorganisms in suitable nutrient solutions. In the chemical synthesis, DL-pantolactone is an important precursor. It is prepared in a multi-stage process from formaldehyde, isobutylaldehyde and cyanide, and in further process steps, the racemic mixture is separated, D-pantolactone is subjected to a condensation reaction with β-alanine, and D-pantothenic acid is obtained in this way.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07338792B2uspto-grants-2008_03