تفاعل #1447111

معادلة التفاعل

Et3N

1-naphthol

phosphorus oxychloride

→

title compound

1-Naphthyl dichlorophosphate

المذيبات

Et2O

ظروف التفاعل

المعالجة

1. 1
   workup.WAITthe resulting solution was left
2. 2
   درجة الحرارةto warm to RT overnight
3. 3
   ترشيحThe white slurry was filtered under an inert atmosphere
4. 4
   أخرىall volatiles were removed

الإجراء التجريبي

To 1-naphthol in Et2O (0.23 M) was added phosphorus oxychloride (1.0 eq.) and the solution was cooled to −78° C. Neat Et3N (1.0 eq) was added and the resulting solution was left to warm to RT overnight. The white slurry was filtered under an inert atmosphere and all volatiles were removed to yield the title compound as a colorless liquid that was used without further purification in the next step. 31P NMR (400 MHz, CDCl3): δ 3.93 ppm.

المصدر