تفاعل #1442515

معادلة التفاعل

3-chloro-4-phenylfuran-2,5-dione

phenyl hydrazine

→

1-Anilino-3-chloro-4-phenylpyrrol-2,5-dione

المذيبات

chloroform

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe mixture was filtered
2. 2
   غسيلwashed three times with sodium bicarbonate solution
3. 3
   تجفيفonce with water, dried over sodium sulfate
4. 4
   تركيزconcentrated under reduced pressure

الإجراء التجريبي

4.14 g (20 mmol) of 3-chloro-4-phenylfuran-2,5-dione were initially charged in 50 ml of chloroform and, at room temperature, admixed dropwise with stirring with 2.16 g (20 mmol) of phenyl hydrazine, and the mixture was stirred at room temperature overnight. The mixture was filtered, washed three times with sodium bicarbonate solution and once with water, dried over sodium sulfate and concentrated under reduced pressure. Yield: 5.4 g of a crystalline solid, m.p. 144-146° C.

المصدر