تفاعل #1375813

معادلة التفاعل

methyl 4-tri-n-butylstannylbenzoate

KOH

acetic acid

water

→

title compound

المردود 90.3%

4-Tri-n-butylstannylbenzoic acid

المردود 90.3%

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe resulting solution was refluxed for 2 hours
2. 2
   درجة الحرارةThe solution was cooled
3. 3
   استخلاصThe solution was then extracted with diethyl ether (80 ml)
4. 4
   غسيلThe ether phase was washed with water (30 ml)
5. 5
   تجفيفdried over MgSO4 (5 g)
6. 6
   ترشيحfiltered
7. 7
   أخرىevaporated under reduced pressure

الإجراء التجريبي

To a solution of methyl 4-tri-n-butylstannylbenzoate (3.0 g, 7 mmol) in absolute ethanol (60 ml) was added 0.25 g KOH (9 mmol). The resulting solution was refluxed for 2 hours. The solution was cooled and poured into an ice-cold solution of acetic acid (0.64 g, 10.6 mmol) and water (100 ml). The solution was then extracted with diethyl ether (80 ml). The ether phase was washed with water (30 ml), dried over MgSO4 (5 g), filtered and evaporated under reduced pressure to afford 2.6 g (88%) of the title compound. This material was used without further purification.

المصدر