تفاعل #1372
ord-1c88fe3c527448899e928f57e94a62f9
معادلة التفاعل
ethyl 2-methyl-3,4,6-trifluorobenzoylacetate
acetic anhydride
triethoxymethane
→
ethyl 2-(2-methyl-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate
المردود 90.0%
الكواشف
لا شيء
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1درجة الحرارةthe mixture is refluxed for 1 hour
- 2تركيزAfter concentrating
الإجراء التجريبي
To ethyl 2-methyl-3,4,6-trifluorobenzoylacetate (3.2 g) are added acetic anhydride (3.0 g) and triethoxymethane (2.7 g) and the mixture is refluxed for 1 hour. After concentrating, ethyl 2-(2-methyl-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate (3.5 g) is obtained.