تفاعل #1367808
ord-6abd913b7cd84d4baff3d8690509089b
معادلة التفاعل
الكواشف
لا شيء
المذيبات
ظروف التفاعل
درجة الحرارة
20°CELSIUS
الظروف التفصيلية
See reaction.notes.procedure_details.
الإجراء التجريبي
The process is performed as in Example 2, starting with 11.39 g of ethyl (2RS)-2-acetylamino-3-(3-cyanophenyl)propanoate, 17.39 g of ammonium hydrogen carbonate and 0.1 g of α-chymotrypsin in 200 cm3 of water and 70 cm3 of acetonitrile. After stirring for 24 hours at a temperature in the region of 20° C. and an identical work-up, 5.40 g of ethyl (2R)-2-acetylamino-3-(3-cyanophenyl)propanoate are obtained in the form of a beige-colored solid. (Rf=0.76 in a 40/10/20 by volume mixture of n-butanol/acetic acid/water, on a Merck 60F254R silica plate)