تفاعل #1367

معادلة التفاعل

2-methylthiomethyl-3,4,6-trifluoroaniline

→

2-methyl-3,4,6-trifluoroaniline

المردود 71.3%

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحAfter the catalyst is filtered off
2. 2
   workup.ADDITIONthe filtrate is added with water
3. 3
   استخلاصextracted with dichloromethane
4. 4
   تجفيفThe is dried over magnesium sulfate
5. 5
   تركيزconcentrated

الإجراء التجريبي

To 2-methylthiomethyl-3,4,6-trifluoroaniline (22.2 g) are added ethanol (400 ml) and Raney nickel (200 g) and the mixture is stirred at room temperature for 30 minutes. After the catalyst is filtered off, the filtrate is added with water and extracted with dichloromethane. The is dried over magnesium sulfate and concentrated to give 2-methyl-3,4,6-trifluoroaniline (12.3 g).

المصدر