تفاعل #1351

معادلة التفاعل

ethanolamine

methyl acetoacetate

→

XXIII

المردود 91.2%

3-(2-Hydroxyethylamino)-but-2-enoic acid methyl ester

المردود 91.2%

ظروف التفاعل

الإجراء التجريبي

To an ice-cooled sample of ethanolamine (6.1 g) was added methyl acetoacetate (11.6 g) dropwise. Compound (XXIII 14.5 g) was formed within 30 min (U.S. Pat. No. 1102800).

المصدر