تفاعل #1350061

معادلة التفاعل

N2 (tert-butyloxycarbonyl)-N-methyl-N-(3-phenylpropyl)-D-methioninamide

Ether

→

N-methyl-N-(3-phenylpropyl)-D-methioninamide

المردود 112.3%

المذيبات

hydrogen chloride-ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   أخرىprecipitating an oil

الإجراء التجريبي

A solution of N2 -(tert-butyloxycarbonyl)-N-methyl-N-(3-phenylpropyl)-D-methioninamide (4.06 g.) in hydrogen chloride-ethyl acetate (3.9 N, 20 ml.) was stirred at room temperature for 40 minutes. Ether (100 ml.) was added, precipitating an oil, and the mixture was stripped of volatiles under vacuum, affording N-methyl-N-(3-phenylpropyl)-D-methioninamide (3.13 g.).

المصدر