تفاعل #1340601

معادلة التفاعل

(3S,4S)-1-benzyloxycarbonyl-3-(tert-butoxycarbonyl)amino-4-ethylpyrrolidine

hydrogen

→

title compound

(3S,4S)-3-(tert-Butoxycarbonyl)amino-4-ethylpyrrolidine

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحAfter filtration
2. 2
   تركيزthe filtrate was concentrated under reduced pressure

الإجراء التجريبي

A 10% palladium carbon catalyst (50 mg) was added to a solution of (3S,4S)-1-benzyloxycarbonyl-3-(tert-butoxycarbonyl)amino-4-ethylpyrrolidine (514 mg, 1.48 mmol) in methanol (15 mL). The resultant mixture was stirred at room temperature for 2 hours under an ordinary pressure in a hydrogen atmosphere. After filtration, the filtrate was concentrated under reduced pressure, to thereby yield the title compound as a colorless oily substance (324 mg, quantitative amount).

المصدر