تفاعل #1340564

معادلة التفاعل

acetyltriphenylene

NaOH

EtOH

I2

I2

→

2-triphenylenecarboxylic acid

acetyltriphenylene

المذيبات

pyridine

water

ظروف التفاعل

المعالجة

1. 1
   أخرىat room temperature
2. 2
   درجة الحرارةat reflux for 45 min
3. 3
   درجة الحرارةAfter reflux for a further hour
4. 4
   درجة الحرارةthe reaction mixture is heated
5. 5
   درجة الحرارةto reflux for 2 h

الإجراء التجريبي

The reaction product obtained in step a) is admixed with 2.2 equivalents of I2 (based on the crude yield of acetyltriphenylene) in pyridine solvent at room temperature. Thereafter, the mixture is kept at reflux for 45 min, and then a further portion of I2 (1.0 equivalent) is added. After reflux for a further hour, NaOH, EtOH and water are added and the reaction mixture is heated to reflux for 2 h. 2-triphenylenecarboxylic acid is obtained in 76% yield (based on crude yield of acetyltriphenylene, or 74% based on triphenylene).

المصدر