تفاعل #1334715

معادلة التفاعل

phytantriol

acetone

→

2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-6,10,14-trimethyl-pentadecan-2-ol

ظروف التفاعل

المعالجة

1. 1
   أخرىfor 15 hr
2. 2
   أخرىAfter the completion of the reaction
3. 3
   أخرىthe acetone solvent was removed under reduced pressure
4. 4
   استخلاصthe resultant was extracted with chloroform solution
5. 5
   غسيلThe extract was washed with saturated sodium bicarbonate solution
6. 6
   غسيلwas again washed with saline

الإجراء التجريبي

One g of phytantriol (3.0 mmol) was refluxed using deanstock apparatus for 15 hr in 25 ml of acetone solution with toluene sulfonic acid as catalyst. After the completion of the reaction, the acetone solvent was removed under reduced pressure and the resultant was extracted with chloroform solution. The extract was washed with saturated sodium bicarbonate solution and was again washed with saline to obtain 0.3 g of (2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-6,10,14-trimethyl-pentadecan-2-ol) of which 1- and 2-positions were protected, which is represented by the following formula (IV):

المصدر