تفاعل #1269886

معادلة التفاعل

(4-phenoxypyridin-3-yl)methanol

→

4-phenoxynicotinaldehyde

المردود 106.5%

المذيبات

THF

ظروف التفاعل

المعالجة

1. 1
   ترشيحthe reaction mixture was filtered (celite)
2. 2
   أخرىRemoval of the solvent

الإجراء التجريبي

MnO2 (289 mg, 3.33 mmol) was added to a solution of (4-phenoxypyridin-3-yl)methanol (70 mg, 0.33 mmol) in THF (10 mL). After stiffing overnight the reaction mixture was filtered (celite). Removal of the solvent provided 4-phenoxynicotinaldehyde (70 mg, 95%). MS [M+H]+=200.1.

المصدر