تفاعل #1269870

معادلة التفاعل

tert-butyl 7-benzoyl-2,7-diazaspiro[4.4]nonane-2-carboxylate

→

phenyl(2,7-diazaspiro[4.4]nonan-2-yl)methanone

المذيبات

TFA

CH2Cl2

ظروف التفاعل

المعالجة

1. 1
   أخرىAfter removal of solvents
2. 2
   أخرىthe residue, phenyl(2,7-diazaspiro[4.4]nonan-2-yl)methanone, was used in the further reactions without purification

الإجراء التجريبي

tert-butyl 7-benzoyl-2,7-diazaspiro[4.4]nonane-2-carboxylate (100 mg) was dissolved in 10% TFA solution in CH2Cl2 (10 mL). The reaction was stirred at room temperature for 24 hours. After removal of solvents, the residue, phenyl(2,7-diazaspiro[4.4]nonan-2-yl)methanone, was used in the further reactions without purification.

المصدر