تفاعل #1269853
ord-02d982387bfb4925a35fe8e398cd0776
معادلة التفاعل
4-((S)-2-amino-4-tert-butoxycarbonyl-butyryl)-piperazine-1-carboxylic acid ethyl ester
TFA
→
desired product
4-((S)-2-Amino-4-carboxy-butyryl)-piperazine-1-carboxylic acid ethyl ester trifluoroacetate salt
الكواشف
لا شيء
المذيبات
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1أخرىThe solution was evaporated to dryness
الإجراء التجريبي
To a solution of 4-((S)-2-amino-4-tert-butoxycarbonyl-butyryl)-piperazine-1-carboxylic acid ethyl ester (0.8 g, prepared as described in WO2006114774) in CH2Cl2 (15 mL) was added TFA (15 mL) and the reaction mixture stirred for 2 h at RT. The solution was evaporated to dryness to give 0.9 g of the desired product as clear oil.