تفاعل #1265401

معادلة التفاعل

compound

5-nitroso-2,6-diamino-4-ethoxy-pyrimidine

sodium dithionite

sodium dithionite

→

title compound

المردود 61.1%

2,5,6-triamino-4-ethoxy-pyrimidine

المردود 61.1%

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   أخرىa yellow solution was formed
2. 2
   أخرىWater was evaporated
3. 3
   أخرىthe resulting residue was precipitated from a small amount of water

الإجراء التجريبي

To a suspension of the compound of example 56 (7.12 g, 38.9 mmoles) in water (150 ml) at 60° C. was added sodium dithionite (46.7 mmol, 8.12 g). Additional sodium dithionite was added till the pink colour completely disappeared and a yellow solution was formed. The solution was stirred at 60° C. for another 4 hours. Water was evaporated and the resulting residue was precipitated from a small amount of water, providing the title compound as a yellow powder (4.02 g, yield 61%). Spectral data are identical with literature data (W. Pfleiderer et al. cited supra).

المصدر