تفاعل #1253203

معادلة التفاعل

chlorine

3,4-dimethyl-2-pyrazolin-5-one

→

3,4-dimethyl-4-chloro-2-pyrazolin-5-one

المذيبات

1,2-dichloroethane

ظروف التفاعل

المعالجة

1. 1
   أخرىAfter the reaction
2. 2
   درجة الحرارةthe reaction mixture was cooled
3. 3
   ترشيحfiltered
4. 4
   workup.DISTILLATIONThe solvent was then distilled off
5. 5
   أخرىThe residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether

الإجراء التجريبي

A chlorine gas was introduced into a solution of 3,4-dimethyl-2-pyrazolin-5-one in 1,2-dichloroethane, followed by gradual refluxing. After the reaction, the reaction mixture was cooled and filtered. The solvent was then distilled off. The residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether, whereby 3,4-dimethyl-4-chloro-2-pyrazolin-5-one was obtained.

المصدر