تفاعل #1244247

معادلة التفاعل

propanoyl chloride

4-Phenylazophenol

triethylamine

→

product

المردود 72.0%

Propionic acid 4-phenylazo-phenyl ester

المردود 72.0%

المذيبات

ether

ether

ظروف التفاعل

المعالجة

1. 1
   أخرىreaction
2. 2
   غسيلThe reaction mixture was washed with water
3. 3
   workup.ADDITIONdilute acid and brine
4. 4
   تجفيفdried with magnesium sulfate
5. 5
   أخرىThe solvent was evaporated

الإجراء التجريبي

4-Phenylazophenol (0.25 g, 1.26 mmoles) was dissolved in ether (5-10 mL) and triethylamine (0.26 mL) was added. Then propanoyl chloride (0.14 g 1.5 mmoles) in ether (1 mL) was added dropwise at room temperature. The mixture was stirred and reaction was rapidly completed. The reaction mixture was washed with water, dilute acid and brine and dried with magnesium sulfate. The solvent was evaporated to give 0.23 g (72%) of product. 1H NMR (CDCl3) δ=1.16 (3H, t, J=7.7), 2.40 (2H, q J=7.7), 7.25 (2H, m), 7.40-7.58 (3H, m), 7.88-8.0 (4H, m) ppm.

المصدر