تفاعل #1235

ord-5fa351dbe3ea452bbf01e7f31dec9368

معادلة التفاعل

COC(=O)c1cc(I)c[nH]1
methyl 4-iodo-2-pyrrolecarboxylate
CCCI
3-iodopropane
CCCn1cc(I)cc1C(=O)OC
methyl N-propyl-4-iodo-2-pyrrolecarboxylate
المردود 64.7%

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

Following the basic procedure of Example 7(d), by reacting 1.96 g (7.8 mmol) of methyl 4-iodo-2-pyrrolecarboxylate with 940 μl (9.6 mmol) of 3-iodopropane, 1.48 g (64%) of methyl N-propyl-4-iodo-2-pyrrolecarboxylate was obtained in the form of a slightly yellow oil.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05723499uspto-grants-1998_03