تفاعل #1196533

معادلة التفاعل

N-bromosuccinimide

2,2-diphenyl-1,3-benzodioxol

→

5-bromo-2,2-diphenyl-1,3-benzodioxol

المذيبات

chloroform

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةat reflux for 20 hours
2. 2
   درجة الحرارةThe reaction mixture was cooled
3. 3
   ترشيحthe separated succinimide was filtered off
4. 4
   غسيلThe filtrate was washed with water
5. 5
   تجفيفdried over sodium sulphate
6. 6
   أخرىthe solvent was removed in a vacuum
7. 7
   أخرىBy crystallization of the residue from ethanol

الإجراء التجريبي

18.75 g of N-bromosuccinimide are added to a solution of 27.4 g of 2,2-diphenyl-1,3-benzodioxol in 80 ml of chloroform and the mixture was boiled at reflux for 20 hours. The reaction mixture was cooled and the separated succinimide was filtered off. The filtrate was washed with water, dried over sodium sulphate and the solvent was removed in a vacuum. By crystallization of the residue from ethanol, there was obtained 5-bromo-2,2-diphenyl-1,3-benzodioxol as white crystals of melting point 88-89° C.

المصدر