تفاعل #11965

معادلة التفاعل

compound

(S)-2-(4-(N-Boc-aminomethyl)benzoylamino)-4-(N-Boc-amino)butyric acid

hydrochloric acid dioxane

→

title compound

المردود 189.4%

(S)-2-(4-aminomethylbenzoylamino)-4-aminobutyric acid

المردود 189.4%

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىAfter the reaction
2. 2
   أخرىthe solvent was removed by distillation
3. 3
   أخرىthe residue was dried

الإجراء التجريبي

The compound obtained in Example 60-2 (49.7 mg) was dissolved in methanol (0.5 ml) and 4 mol/l hydrochloric acid/dioxane solution (0.5 ml) was added. The mixture was stirred for 1.5 hours at room temperature. After the reaction, the solvent was removed by distillation and the residue was dried using a vacuum pump to obtain the title compound (52.4 mg) as a white solid.

المصدر