تفاعل #11906

ord-e737455c44f54ee7a737fd439bc448cd

معادلة التفاعل

O=C(O)C1CN(C(=O)OCc2ccccc2)CCN1c1c([N+](=O)[O-])ccc(Cl)c1Cl
4-carbobenzyloxy-1-(5,6-dichloro-2-nitrophenyl)piperazine-2-carboxylic acid
O=C1Nc2ccc(Cl)c(Cl)c2N2CCN(C(=O)OCc3ccccc3)CC12
desired product
المردود 50.7%
O=C1Nc2ccc(Cl)c(Cl)c2N2CCN(C(=O)OCc3ccccc3)CC12
3-Carbobenzyloxy-9,10-Dichloro-2,3,4,4a-Tetrahydro-1H-Pyrazino[1,2-a]-Quinoxalin-5(6H)-One
المردود 50.7%

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

By the same procedure described for Example 7B, from 0.75 g of 4-carbobenzyloxy-1-(5,6-dichloro-2-nitrophenyl)piperazine-2-carboxylic acid and 0.28 g of iron powder, there was obtained 0.34 g (49%) of the desired product as a brown solid.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07098338B2uspto-grants-2006_08