تفاعل #1178397

معادلة التفاعل

p-methoxybenzophenone

→

1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene

المردود 91.0%

المذيبات

THF

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas refluxed for 20 h
2. 2
   ترشيحfiltered
3. 3
   أخرىThe filtrates were evaporated
4. 4
   أخرىthe crude product was purified by a silica gel column

الإجراء التجريبي

A suspension of p-methoxybenzophenone (1.06 g, 5.0 mmol), 1.34 equiv of TiCl3/AlCl3 (5.81 g, 6.7 mmol), and 25 equiv of Zn dust (8.01 g, 122.0 mmol) in 100 ml of dry THF was refluxed for 20 h. The reaction mixture was cooled to room temperature and filtered. The filtrates were evaporated and the crude product was purified by a silica gel column using hexane as eluent. 1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene (TPE-OMe) was isolated in 91% yield.

المصدر