تفاعل #1166468

معادلة التفاعل

2-(aminoethoxy)ethanol

hexahydrophthalic anhydride

→

N-(2-hydroxyethoxyethyl)hexahydrophthalimide

المردود 96.0%

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   أخرىA 500-ml, two necked flask was equipped with a magnetic stirring bar
2. 2
   درجة الحرارةheating mantle and condenser
3. 3
   workup.ADDITIONAfter the addition
4. 4
   درجة الحرارةwas refluxed for 12 hours
5. 5
   أخرىThe ethanol was removed with a rotoevaporator

الإجراء التجريبي

A 500-ml, two necked flask was equipped with a magnetic stirring bar, heating mantle and condenser. The flask was charged with 51 g of 2-(aminoethoxy)ethanol (0.49 mol.) and 250 ml of ethanol. Next, 75 g of hexahydrophthalic anhydride (0.49 mol.) was slowly added to the flask. After the addition was complete the reaction was refluxed for 12 hours. The IR spectrum indicated the reaction was complete. The ethanol was removed with a rotoevaporator to yield 113 g (96%) of N-(2-hydroxyethoxyethyl)hexahydrophthalimide.

المصدر