تفاعل #1157
ord-95e24e77c6ef45318b9ed18596119d65
معادلة التفاعل
(E)-ethyl 3-[5-(5-methyl-2-phenyl-4-oxazolylmethoxy)-2-benzofuranyl]acrylate
diisobutylaluminum hydride
→
(E)-3-[5-(5-methyl-2-phenyl-4-oxazolylmethoxy)-2-benzofuranyl]-2-propen-1-ol
المردود 90.0%
المتفاعلات
الكواشف
لا شيء
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
الإجراء التجريبي
In the same manner as in Reference Example 11, (E)-ethyl 3-[5-(5-methyl-2-phenyl-4-oxazolylmethoxy)-2-benzofuranyl]acrylate was reduced with diisobutylaluminum hydride to yield (E)-3-[5-(5-methyl-2-phenyl-4-oxazolylmethoxy)-2-benzofuranyl]-2-propen-1-ol (yield 90%), which was then recrystallized from ethyl acetate-hexane to yield colorless prisms having a melting point of 145° to 146° C.