تفاعل #1145322

ord-57797cd706a04eedba1123ef9af188c6

معادلة التفاعل

Cc1cc(S(C)(=O)=O)c(S(C)(=O)=O)cc1C(=O)Cl
2-methyl-4,5-di(methylsulfonyl)benzoyl chloride
NC(N)=[NH2+].[Cl-]
guanidinium chloride
→
Cc1cc(S(C)(=O)=O)c(S(C)(=O)=O)cc1C(=O)N=C(N)N
N-diaminomethylene-2-methyl-4,5-di(methylsulfonyl)benzamide

المتفاعلات

Cc1cc(S(C)(=O)=O)c(S(C)(=O)=O)cc1C(=O)Cl
2-methyl-4,5-di(methylsulfonyl)benzoyl chloride
NC(N)=[NH2+].[Cl-]
guanidinium chloride

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

in stage e) finally, as described in EP 0 758 644 (p.9, lines 10-20), by reaction of 2-methyl-4,5-di(methylsulfonyl)benzoyl chloride with guanidinium chloride to give the end-product N-diaminomethylene-2-methyl-4,5-di(methylsulfonyl)benzamide, the guanidino group is introduced.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US06515143B2uspto-grants-2003_02