تفاعل #1144428

معادلة التفاعل

1-(methoxymethyl)-6-phenylthiothymine

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target compound

المردود 28.1%

6-phenylthiothymine

المردود 28.1%

المذيبات

hydrochloric acid

ظروف التفاعل

المعالجة

1. 1
   أخرىto react for 2 hours at 80° C
2. 2
   تركيزThe reaction mixture was concentrated under reduced pressure
3. 3
   أخرىcrystallized from ethanol

الإجراء التجريبي

To 100 ml of concentrated hydrochloric acid, 17.2 g (62 mmole) of 1-(methoxymethyl)-6-phenylthiothymine was added and allowed to react for 2 hours at 80° C. The reaction mixture was concentrated under reduced pressure and crystallized from ethanol to obtain 3.8 g of the target compound (Yield: 26%).

المصدر