تفاعل #1135811

معادلة التفاعل

1-(2-methoxymethyl-3-ethenylphenyl)-4-methyl-1,4-dihydrotetrazole-5-one

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1-(2-methoxymethyl-3-ethylphenyl)-4-methyl-1,4-dihydrotetrazole-5-one

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىThe reaction mixtures
2. 2
   ترشيحwere filtered
3. 3
   تركيزthe filtrates were concentrated under reduced pressure

الإجراء التجريبي

A mixture of 1-(2-methoxymethyl-3-ethenylphenyl)-4-methyl-1,4-dihydrotetrazole-5-one described in Reference Preparation example 2219.7 g, palladium fibroin complex 3.02 g and methanol 1 L was stirred at room temperature under hydrogen atmosphere for eleven hours. The reaction mixtures were filtered and the filtrates were concentrated under reduced pressure. The resulting residues were subjected to a silica gel column chromatography to give 1-(2-methoxymethyl-3-ethylphenyl)-4-methyl-1,4-dihydrotetrazole-5-one 19.3 g.

المصدر