تفاعل #1135800

معادلة التفاعل

1-bromo-2-methyl-3-aminobenzene

triphosgene

→

1-bromo-3-isocyanato-2-methylbenzene

المردود 106.3%

المذيبات

toluene

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwith heating
2. 2
   درجة الحرارةunder reflux for three hours
3. 3
   درجة الحرارةto cool
4. 4
   تركيزwere concentrated under reduced pressure

الإجراء التجريبي

A mixture of 1-bromo-2-methyl-3-aminobenzene 25.0 g, triphosgene 60.0 g and toluene 400 mL was stirred with heating under reflux for three hours. The reaction mixtures after standing to cool were concentrated under reduced pressure to give 1-bromo-3-isocyanato-2-methylbenzene 30.3 g.

المصدر