تفاعل #11356

معادلة التفاعل

2-hydroxybenzonitrile

potassium carbonate

ethyl bromide

→

2-Ethoxybenzonitrile

المذيبات

acetone

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe solid is filtered off
2. 2
   أخرىthe solvent is removed under reduced pressure
3. 3
   workup.DISTILLATIONthe residue is distilled under reduced pressure

الإجراء التجريبي

25 g (210 mmol) of 2-hydroxybenzonitrile, 87 g of potassium carbonate and 34.3 g (314.8 mmol) of ethyl bromide are refluxed in 500 ml of acetone overnight. The solid is filtered off, the solvent is removed under reduced pressure and the residue is distilled under reduced pressure. This gives 30.0 g (97%) of a colorless liquid.

المصدر