تفاعل #11071

معادلة التفاعل

intermediate 19b

3-benzyloxycarbonylamino-6-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid

intermediate 20a

6-allyl-3-benzyloxycarbonylamino-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid tert-butyl ester

→

intermediate 20b

المردود 86.3%

6-allyl-3-benzyloxycarbonylamino-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid

المردود 86.3%

ظروف التفاعل

الإجراء التجريبي

According to the procedure for the preparation of intermediate 19b, intermediate 20a (127 mg, 0.298 mmol) was deprotected to afford 95 mg (86%) of intermediate 20b. MS (ESI) 368.2 (M−H+).

المصدر