تفاعل #11040

معادلة التفاعل

2,7-dichloromethyl-3,6-di-t-butylfluorene

LiAlH4

→

2,7-di-methyl-3,6-di-tert-butyl-fluorene

المردود 85.0%

المذيبات

THF

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةthe mixture was refluxed for 4 hours
2. 2
   أخرىThe reaction was quenched with water and NaOH
3. 3
   استخلاصextracted with ether
4. 4
   أخرىThe ether solution was evaporated under vacuum

الإجراء التجريبي

To a solution of 2,7-dichloromethyl-3,6-di-t-butylfluorene (0.75 g, 2.0 mmol) in THF (15 ml) was added a small portion of LiAlH4 (220 mg, 5.8 mmol) under stirring and the mixture was refluxed for 4 hours. The reaction was quenched with water and NaOH and extracted with ether. The ether solution was evaporated under vacuum to give a white solid of 2,7-di-methyl-3,6-di-tert-butyl-fluorene with a yield of 85%.

المصدر