تفاعل #10681

معادلة التفاعل

2-(2-bromoethoxy)tetrahydro-2H-pyran

compound

trans-N-(5-isoquinolyl)-1,4-cyclohexanediamine hydrochloride

→

title compound

Trans-N-(5-isoquinolyl)-N′-(2-hydroxyethyl)-1,4-cyclohexanediamine hydrochloride

ظروف التفاعل

المعالجة

1. 1
   أخرىa deprotection reaction

الإجراء التجريبي

According to the method of Example 144, an alkylation reaction with 2-(2-bromoethoxy)tetrahydro-2H-pyran and a deprotection reaction were performed by using the compound of Example 24 to obtain the title compound.

المصدر