تفاعل #10680

معادلة التفاعل

2-(2-bromoethoxy)tetrahydro-2H-pyran

compound

4-(4-methyl-5-isoquinolyl)aminopiperidine hydrochloride

→

title compound

1-(2-Hydroxyethyl)-4-(4-methyl-5-isoquinolyl)aminopiperidine hydrochloride

ظروف التفاعل

المعالجة

1. 1
   أخرىa deprotection reaction

الإجراء التجريبي

According to the method of Example 144, an alkylation reaction with 2-(2-bromoethoxy)tetrahydro-2H-pyran and a deprotection reaction were performed by using the compound of Example 106 to obtain the title compound.

المصدر