تفاعل #1052049

معادلة التفاعل

Tetrafluorophthalic anhydride

N,N-dimethylformamide

pyridine

hydrazine

→

Compound 43

المردود 87.0%

tetrafluorophthalhydrazide

المردود 87.0%

ظروف التفاعل

المعالجة

1. 1
   تركيزThe reaction mixture is concentrated in vacuo
2. 2
   workup.ADDITIONthe residue is poured into water (200 mL)
3. 3
   أخرىThe precipitate formed
4. 4
   ترشيحis collected by filtration
5. 5
   غسيلwashed with water
6. 6
   أخرىair-dried

الإجراء التجريبي

Tetrafluorophthalic anhydride (400 mg, 1.8 mmol) is dissolved in 10 mL of anhydrous N,N-dimethylformamide (DMF) that contains anhydrous pyridine (0.47 mL, 5.8 mmol). To the solution is slowly added hydrazine (64 mg, 2.0 mmol). The resulting mixture is stirred overnight. The reaction mixture is concentrated in vacuo, and the residue is poured into water (200 mL). The precipitate formed is collected by filtration, washed with water and air-dried to give Compound 43 (369 mg, yield: 87%).

المصدر