تفاعل #1010883

معادلة التفاعل

carbazole

1-bromo-2-iodobenzene

potassium carbonate

→

9-(2-bromophenyl)-9H-carbazole

المذيبات

xylene

ظروف التفاعل

المعالجة

1. 1
   استخلاصextracted with ethyl acetate
2. 2
   تجفيفdried with anhydrous magnesium sulfate
3. 3
   أخرىto remove moisture
4. 4
   أخرىthe solvent was removed under reduced pressure
5. 5
   أخرىSilica gel column separation
6. 6
   أخرىthus obtaining a compound from which the solvent
7. 7
   أخرىwas then removed under reduced pressure
8. 8
   أخرىdrying

الإجراء التجريبي

1.672 g of carbazole, 1.6 mL of 1-bromo-2-iodobenzene, 2.7646 g of potassium carbonate, 95 mg of copper iodide and 25 mL of xylene were refluxed in a nitrogen atmosphere. The mixture was cooled to room temperature, extracted with ethyl acetate, and dried with anhydrous magnesium sulfate to remove moisture, and the solvent was removed under reduced pressure. Silica gel column separation using a hexane solvent was conducted, thus obtaining a compound from which the solvent was then removed under reduced pressure, followed by vacuum drying, yielding 9-(2-bromophenyl)-9H-carbazole as a desired white solid intermediate.

المصدر