تفاعل #1001669

معادلة التفاعل

2-[(4-{2-[(5-ethylpyrimidin-2-yl)amino]ethyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester

(3-bromopropyl)benzene

hydrobromic acid acetic acid

→

title compound

2-[(4-{2-[(5-ethylpyrimidin-2-yl)(3-phenylpropyl)amino]ethyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid hydrogen bromide

المذيبات

diethyl ether

ظروف التفاعل

المعالجة

1. 1
   أخرىA compound obtained

الإجراء التجريبي

A compound obtained using 2-[(4-{2-[(5-ethylpyrimidin-2-yl)amino]ethyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester synthesized in Example 265-1 and (3-bromopropyl)benzene as starting materials and by an operation similar to that of Example 326 was dissolved in diethyl ether, and reacted with 30% hydrobromic acid-acetic acid to give the title compound.

المصدر