تفاعل #1000784

معادلة التفاعل

4-chloro-2-propyl-1H-indole-5-carbonitrile

5-[3,5-bis(trifluoromethyl)phenyl]-3-(chloromethyl)-1,2,4-oxadiazole

→

1-({5-[3,5-bis(Trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-chloro-2-propyl-1H-indole-5-carbonitrile

ظروف التفاعل

المعالجة

1. 1
   أخرىSynthesized

الإجراء التجريبي

Synthesized as described in Example 4 from 4-chloro-2-propyl-1H-indole-5-carbonitrile and 5-[3,5-bis(trifluoromethyl)phenyl]-3-(chloromethyl)-1,2,4-oxadiazole: 1H NMR (400 MHz, DMSO-d6) δ 8.53 (s, 2 H), 8.50 (s, 1 H), 7.96 (s, 1 H), 7.77 (d, J=8.7 Hz, 1 H), 7.59 (d, J=8.7 Hz, 1 H), 5.87 (s, 2 H), 2.97-2.82 (m, 2 H), 1.70-1.56 (m, 2 H), 0.97-0.89 (m, 3 H); MS (ES) m/z 513 (M+1).

المصدر