بحث البنية الفرعية

753872

COc1ccc(CN(c2ccccc2)c2cc(Cl)nn3ccnc23)cc1
Reaction #182552
DOI: 10.1039/C8SC04228D
COc1ccc(CN(c2cc(Cl)nn3c(C(=O)Nc4ccnc(Cl)c4)cnc23)C2CC2)cc1
Reaction #200303
DOI: 10.1039/C8SC04228D
COc1ccc(CN(c2ccccn2)c2cc(Cl)nn3c(C(=O)Nc4ccncc4F)cnc23)cc1
Reaction #207003
DOI: 10.1039/C8SC04228D
COc1ccc(CN(c2cc(Cl)nn3c(C(=O)Nc4ccnc(F)c4)cnc23)C2CC2)cc1
Reaction #208698
DOI: 10.1039/C8SC04228D
O=C(Nc1ccncc1F)c1cnc2c(Nc3ccc(F)cn3)cc(Cl)nn12
Reaction #225745
DOI: 10.1039/C8SC04228D
Cn1ccc(Nc2cc(Cl)nn3c(C(=O)Nc4ccncc4F)cnc23)n1
Reaction #239729
DOI: 10.1039/C8SC04228D
O=C(Nc1ccncc1F)c1cnc2c(Nc3ccon3)cc(Cl)nn12
Reaction #265242
DOI: 10.1039/C8SC04228D
CCOC(=O)c1cnc2c(Cl)cc(Cl)nn12
Reaction #269474
DOI: 10.1039/C8SC04228D
CNS(=O)(=O)c1ccc(Nc2cc(Cl)nn3c(Br)cnc23)cc1
Reaction #270874
DOI: 10.1039/C8SC04228D
Fc1cccc(F)c1Nc1cc(Cl)nn2ccnc12
Reaction #279286
DOI: 10.1039/C8SC04228D
COc1ccc(CN(c2ccc(C)cn2)c2cc(Cl)nn3ccnc23)cc1
Reaction #290737
DOI: 10.1039/C8SC04228D
O=C(Nc1ccncc1)c1cnc2c(Br)cc(Cl)nn12
Reaction #295841
DOI: 10.1039/C8SC04228D
Nc1cc(Cl)cc(Nc2cc(Cl)nn3c(C(=O)Nc4ccncc4F)cnc23)n1
Reaction #302089
DOI: 10.1039/C8SC04228D
O=C(c1ccc(Nc2cc(Cl)nn3ccnc23)nc1)N1CCOCC1
Reaction #490111
[6-(6-chloro-imidazo[1,2-b]pyridazin-8-ylamino)-pyridin-3-yl]-morpholin-4-yl-methanone
المردود 100.1%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)N1CCN(c2ccc(Nc3cc(Cl)nn4ccnc34)nc2)CC1
Reaction #490112
(6-chloro-imidazo[1,2-b]pyridazin-8-yl)-[5-(4-isopropyl-piperazin-1-yl)-pyridin-2-yl]-amine
المردود 24.3%DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(Cc2ccc(Nc3cc(Cl)nn4ccnc34)nc2)CC1
Reaction #490115
(6-chloro-imidazo[1,2-b]pyridazin-8-yl)-[5-(4-methyl-piperazin-1-ylmethyl)-pyridin-2-yl]-amine
المردود 51.6%DOI: 10.6084/m9.figshare.5104873.v1
O=C(Nc1ccncc1F)c1cnc2c(Br)cc(Cl)nn12
Reaction #759700
DOI: 10.1039/C8SC04228D
CCNc1cc(Cl)nn2c(C(=O)Nc3ccncc3F)cnc12
Reaction #772708
DOI: 10.1039/C8SC04228D
CCc1c(Cl)nn2ccnc2c1Nc1ccccc1
Reaction #782568
DOI: 10.1039/C8SC04228D
CCOC(=O)c1cn2nc(Cl)cc(Br)c2n1
Reaction #805747
compound 5a
DOI: 10.6084/m9.figshare.5104873.v1
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