بحث البنية الفرعية

409605

CC(C)(C)OC(=O)N1CCC(c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)N(C(=O)OC(C)(C)C)c3cscn3)cc2Cl)CC1
Reaction #74510
tert-butyl 4-[2-(4-{[(tert-butoxycarbonyl)(1,3-thiazol-4-yl)amino]sulfonyl}-2-chloro-5-fluorophenoxy)-5-chlorophenyl]piperidine-1-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(CN(c2ncns2)S(=O)(=O)c2cc(Cl)c(Oc3ccc(Cl)cc3C3CCN(C(=O)OC(C)(C)C)CC3)cc2F)c(OC)c1
Reaction #74523
tert-butyl 4-[5-chloro-2-(2-chloro-4-{[(2,4-dimethoxybenzyl)(1,2,4-thiadiazol-5-yl)amino]sulfonyl}-5-fluorophenoxy)phenyl]piperidine-1-carboxylate
المردود 97.6%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(Cl)cc1C1CCN(C(=O)OCc2ccccc2)CC1
Reaction #74587
title compound
المردود 77.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(Cl)cc1C1(O)CCN(C(=O)OC(C)(C)C)CC1
Reaction #74588
title compound
المردود 39.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(Cl)cc1C1(OC)CCN(C(=O)OC(C)(C)C)CC1
Reaction #292252
DOI: 10.1039/C8SC04228D
COc1c(C(C)N)cc(Cl)c(C)c1C1CCN(C(=O)OC(C)(C)C)CC1
Reaction #598147
crude desired product
المردود 101.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1c(C(C)Nc2ncnc3c2ncn3C2CCCCO2)cc(Cl)c(C)c1C1CCN(C(=O)OC(C)(C)C)CC1
Reaction #598149
desired product
المردود 109.0%DOI: 10.6084/m9.figshare.5104873.v1
Cl
Reaction #598150
HCl
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(Cl)cc1C1(O)CCN(C(=O)OC(C)(C)C)CC1
Reaction #894703
DOI: 10.1039/C8SC04228D
COc1ccc(CN(c2ncns2)S(=O)(=O)c2cc(Cl)c(Oc3ccc(Cl)cc3C3CCN(C(=O)OC(C)(C)C)CC3)cc2F)c(OC)c1
Reaction #1226172
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N1CCC(c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)N(C(=O)OC(C)(C)C)c3cscn3)cc2Cl)CC1
Reaction #1228148
DOI: 10.1039/C8SC04228D
COc1ccc(Cl)cc1C1(OC)CCN(C(=O)OC(C)(C)C)CC1
Reaction #1448698
4-(5-chloro-2-methoxy-phenyl)-4-methoxy-piperidine-1-carboxylic acid tert-butyl ester
المردود 73.6%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(Cl)cc1C1(OC)CCNCC1
Reaction #1448699
4-(5-chloro-2-methoxyphenyl)-4-methoxypiperidine
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N1CCC(c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)N(C(=O)OC(C)(C)C)c3cscn3)cc2Cl)CC1
Reaction #1489081
tert-butyl 4-[2-(4-{[(tert-butoxycarbonyl)(1,3-thiazol-4-yl)amino]sulfonyl}-2-chloro-5-fluorophenoxy)-5-chlorophenyl]piperidine-1-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(CN(c2ncns2)S(=O)(=O)c2cc(Cl)c(Oc3ccc(Cl)cc3C3CCN(C(=O)OC(C)(C)C)CC3)cc2F)c(OC)c1
Reaction #1489094
tert-butyl 4-[5-chloro-2-(2-chloro-4-{[(2,4-dimethoxybenzyl)(1,2,4-thiadiazol-5-yl)amino]sulfonyl}-5-fluorophenoxy)phenyl]piperidine-1-carboxylate
المردود 97.6%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(Cl)cc1C1CCN(C(=O)OCc2ccccc2)CC1
Reaction #1489157
title compound
المردود 77.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(Cl)cc1C1(O)CCN(C(=O)OC(C)(C)C)CC1
Reaction #1489158
title compound
المردود 39.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1c(C(C)=O)cc(Cl)c(C)c1C1CCN(C(=O)OC(C)(C)C)CC1
Reaction #1587002
tert-Butyl 4-(3-acetyl-5-chloro-2-methoxy-6-methylphenyl)piperidine-1-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1
COc1c(C(C)O)cc(Cl)c(C)c1C1CCN(C(=O)OC(C)(C)C)CC1
Reaction #1587003
tert-Butyl 4-[3-chloro-5-(1-hydroxyethyl)-6-methoxy-2-methylphenyl]piperidine-1-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1
COc1c(C(C)Cl)cc(Cl)c(C)c1C1CCN(C(=O)OC(C)(C)C)CC1
Reaction #1587004
tert-Butyl 4-[3-chloro-5-(1-chloroethyl)-6-methoxy-2-methylphenyl]piperidine-1-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1
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