1-(3-amino-pyrazol-1-yl)-2-methyl-propan-2-ol

CCOc1ccccc1OC1=CC(=O)N([C@@H](CC(C)C)C(=O)Nc2ccn(CC(C)(C)O)n2)C1

Reaction #47297

(S)-2-[4-(2-ethoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-amide

DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(O)Cn1ccc(NC(=O)[C@H](CC2CCCC2)N2CC(Oc3c(F)cccc3F)=CC2=O)n1

Reaction #47300

(S)-3-cyclopentyl-2-[4-(2,6-difluoro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-propionamide

المردود 34.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(O)Cn1ccc(NC(=O)[C@H](CC2CCCCO2)NC(=O)OC(C)(C)C)n1

Reaction #47310

[(S)-1-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-ylcarbamoyl]-2-(tetrahydro-pyran-2-yl)-ethyl]-carbamic acid t-butyl ester

المردود 57.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CCO[C@H](C)C[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccn(CC(C)(C)O)n1

Reaction #47316

{(1S,3R)-3-ethoxy-1-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-ylcarbamoyl]-butyl}-carbamic acid t-butyl ester

المردود 73.8%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CCO[C@@H](C)C[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccn(CC(C)(C)O)n1

Reaction #47321

{(1S,3S)-3-ethoxy-1-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-ylcarbamoyl]-butyl}-carbamic acid t-butyl ester

المردود 80.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CCOc1cccc(OC2=CC(=O)N([C@@H](CC(C)C)C(=O)Nc3ccn(CC(C)(C)O)n3)C2)c1F

Reaction #47391

(S)-2-[4-(3-ethoxy-2-fluoro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-amide

المردود 55.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

Cc1ccccc1OC1=CC(=O)N([C@@H](CC(C)C)C(=O)Nc2ccn(CC(C)(C)O)n2)C1

Reaction #47408

(S)-4-methyl-2-(2-oxo-4-o-tolyloxy-2,5-dihydro-pyrrol-1-yl)-pentanoic acid [1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-amide

المردود 36.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)C[C@@H](C(=O)Nc1ccn(CC(C)(C)O)n1)N1CC(Oc2cccc(O)c2F)=CC1=O

Reaction #47413

(S)-2-[4-(2-fluoro-3-hydroxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-amide

المردود 67.9%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CCOc1cccc(OC2=CC(=O)N([C@@H](CC(C)C)C(=O)Nc3ccn(CC(C)(C)O)n3)C2)c1

Reaction #47460

(S)-2-[4-(3-ethoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-amide

المردود 51.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

COc1cccc(OC2=CC(=O)N([C@@H](CC(C)C)C(=O)Nc3ccn(CC(C)(C)O)n3)C2)c1

Reaction #47461

(S)-2-[4-(3-methoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-amide

المردود 79.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)C[C@@H](C(=O)Nc1ccn(CC(C)(C)O)n1)N1CC(Oc2ccccc2F)=CC1=O

Reaction #47462

(S)-2-[4-(2-fluoro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-amide

المردود 74.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

COc1cccc(OC2=CC(=O)N(C(CC(C)(C)F)C(=O)Nc3ccn(CC(C)(C)O)n3)C2)c1Cl

Reaction #47464

2-[4-(2-chloro-3-methoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-fluoro-4-methyl-pentanoic acid [1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-amide

المردود 57.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)Oc1ccccc1OC1=CC(=O)N([C@@H](CC2CCCCC2)C(=O)Nc2ccn(CC(C)(C)O)n2)C1

Reaction #47488

(S)-3-cyclohexyl-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-2-[4-(2-isopropoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-propionamide

المردود 34.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CSc1ccccc1OC1=CC(=O)N([C@@H](CC2CCCCC2)C(=O)Nc2ccn(CC(C)(C)O)n2)C1

Reaction #47493

(S)-3-cyclohexyl-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-2-[4-(2-methylsulfanyl-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-propionamide

المردود 15.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CCCc1ccccc1OC1=CC(=O)N([C@@H](CC2CCCCC2)C(=O)Nc2ccn(CC(C)(C)O)n2)C1

Reaction #47502

(S)-3-cyclohexyl-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-2-[2-oxo-4-(2-propyl-phenoxy)-2,5-dihydro-pyrrol-1-yl]-propionamide

المردود 29.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

COc1cccc(OC2=CC(=O)N([C@@H](CC3CCCCC3)C(=O)Nc3ccn(CC(C)(C)O)n3)C2)c1OC

Reaction #47507

(S)-3-cyclohexyl-2-[4-(2,3-dimethoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-propionamide

المردود 42.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(O)Cn1ccc(NC(=O)[C@H](CC2CCCCC2)N2CC(Oc3cccc(F)c3F)=CC2=O)n1

Reaction #47512

(S)-3-cyclohexyl-2-[4-(2,3-difluoro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-propionamide

المردود 40.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(O)Cn1ccc(NC(=O)[C@H](CC2CCCCC2)N2CC(Oc3cc(Cl)ccc3Cl)=CC2=O)n1

Reaction #47517

(S)-3-cyclohexyl-2-[4-(2,5-dichloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-propionamide

المردود 30.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(O)Cn1ccc(NC(=O)[C@H](CC2CCCCC2)N2CC(Oc3ccc(Cl)cc3Cl)=CC2=O)n1

Reaction #47522

(S)-3-cyclohexyl-2-[4-(2,4-dichloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-propionamide

المردود 35.5%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(O)Cn1ccc(NC(=O)[C@H](CC2CCCCC2)N2CC(Oc3ccccc3OCc3ccccc3)=CC2=O)n1

Reaction #47527

(S)-2-[4-(2-benzyloxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-3-cyclohexyl-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-propionamide

المردود 33.8%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

الصفحة 1التالي